I must say that this wasn’t my first choice of motherboard for 2 reasons:
Firstly, I have had 2 Asus motherboards die on me in the past (one was a slow death as the memory slots failed one by one).
Secondly I was concerned about the layout. The alternate board I looked at was a Gigabyte one which for me would have been better laid out. The reason is that I have 3 PCI TV cards in the HTPC and only one small PCI-e card (Wi-Fi). The PCI TV cards are right against a passively cooled Nvidia 8500GT based graphics card so I am a little worried about airflow and cooling. So far though, I have not had a problem and the board is performing fine.